The story takes place 139 years after the events of Doom and after the destruction of the Union Aerospace Corporation. A very powerful organization collectively called the Zorax Sovereignty, assigns a team of 5 highly skilled engineers to manufacture a Facility on Mars called the 'Blacksite'. The motive to create the Blacksite facility was to further the research for     Argone Bloodline. This Blood combines the blood of advanced Cacodemons and humans. People of the Argone bloodline are superior to a demon and Human. However, Argone blood can only be harvested from Hell. One of the engineers (Turaga) found a way to open a hell portal to harvest Argone Blood and bring it back to earth so he sell it to the now called New Russian Federation.

​

Turaga was able to harvest about 10 litres of Argone blood until the portal became unstable and all hell broke loose which corrupted the other engineers. Pratap , who constructed the BioLab chopped of Turaga’s hand and threw it into the hell portal, sealing away any further Argone Blood transport between hell and Earth. Enraged by it, Turaga attacks Pratap until Zach Intervenes who turns out to be a New Russian Federation Spy. He brutally murders Pratap.

 

A war breaks out between all the 5 engineers, all of whom are possessed by the demonic invasion. Everyone dies, except for one. As this one engineer finds himself waking up in hell. You, the player are playing as Belime as he escapes the Blacksite facility which he once was involved in the construction.